ICCS2004 Application Submission/Review

Abstract for
"The effect of minus ends on the microtubule steady state"


Dynamic instability describes microtubule assembly in which individual microtubules exhibit alternating phases of elongation and rapid shortening. This dynamic is significantly different for the plus and minus ends of a microtubule. In this work, by considering the contribution of the plus and minus ends, we have investigated the behavior of T-tubulin concentration in the steady state and while being disturbed by the small perturbation.